Hi Jojo7,
I've been running in Nike Vomeros for many years. I currently have the Vomero 5. I haven't had the opportunity to try the Vomero 6 yet.
I've been very happy with my Vomeros. If fitted properly, the shoe is very comfortable. I run about 20-30 miles/week. The shoes hold up well.
I'm currently training for a half marathon. These are the shoes I use for training and the run. They are very comfortable at the beginning and end of the run. The longest run I've done so far with them is 10 miles. The shoes keep your feet cool for the run.
The shoes are also Nike+ compatable. Nike+ allows you to track your runs (distance, time, pace, etc.) with a variety of devises (Nike Sportband, ipod nano, iphone, etc). It's a really cool system.
I hope that helps.
If you'd like you could always check out Nike's website for other user reviews.
Cheers,
Victor