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36 Replies Last post: Aug 15, 2007 4:34 PM by DavidD063   Go to original post 1 2 3 Previous Next
Click to view Jim24315's profile Legend 1,937 posts since
Dec 14, 2007
15. Dec 26, 2007 5:20 AM in response to: xWeaselx
Re: Anti-inflammatory medicine
I don't know that NSAIDS would cause kidney cancer--they probably don't. However, there is not much doubt that they can damage the kidneys. I remember an attorney back in Phoenix who popped Advil before every run and ended up on dialysis, nearly losing his life in the process. The doctors said the damage was caused by inbuprofen. Although he survived, he had to give up running.



http://This message has been edited by Jim24315 (edited Aug-10-2007).
Click to view gbroooks's profile Amateur 29 posts since
Jul 19, 2007
16. Aug 10, 2007 11:42 AM in response to: xWeaselx
Re: Anti-inflammatory medicine
NSAID can and should be used to heal a specific injury, provided they are used under the direction of a physician.

Rule of thumb - don't take them because you have a tweak or knot - use ice and massage instead.

But - if you have an acute injury that has produced swelling and increased friction, RICE, along with therapeutic doses of NSAID for 2 weeks is a perfectly acceptable (and wise) treatment option.

Horror stories about rare side effects can be found with any substance - including milk and peanut butter among many others. So I wouldn't exclude the use of a proven injury treatment because there is a 1 in a gazillion chance you're going to have organ failure of some kind. There is a chance that general anesthesia will kill you - that wouldn't stop me from getting an apendectomy...or any other needed treatment, for that matter.

Just don't use them as a crutch - use them to treat a specific injury for a prescribed amount of time and dosage. And of course, if you don't tolerate them well, see your doc for alternatives.
Click to view AndyHass's profile Legend 1,385 posts since
Dec 14, 2007
17. Dec 26, 2007 5:20 AM in response to: xWeaselx
Re: Anti-inflammatory medicine
quote:<HR>Originally posted by Jim24315:
I don't know that NSAIDS would cause kidney cancer--they probably don't. However, there is not much doubt that they can damage the kidneys. I remember an attorney back in Phoenix who popped Advil before every run and ended up on dialysis, nearly losing his life in the process. The doctors said the damage was caused by inbuprofen. Although he survived, he had to give up running.



http://This message has been edited by Jim24315 (edited Aug-10-2007).
<HR>


It's pretty clear why this happened. #1, he was doing it for every run, which is NOT how these drugs are supposed to be used. They are for acute pain, not chronic use. #2, he's taking it and then going for a run in a desert region!! Dehyrdation massively increases the risk of kidney damage. Combine the two......

Read the full label for ANY drug. You'll never take anything if you do that. It's a symptom of our litigious society.....put so many warnings on EVERYTHING that you never know where the real danger and risks lie.
Click to view slikgirl75's profile Amateur 36 posts since
Aug 2, 2007
18. Aug 10, 2007 12:53 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
I would avoid using Advil, Ibuprofen or Excedrin for any length of time. Only once in a great while. Tylenol is better if you really, really have to use anything for pain relief. My Mother was taking Excedrin and Alleve for a very long time. She is a faux finisher by trade, so she was allways popping these due to her hands hurting. She started having acid reflux so bad that she was living on Prilosec and absolutely could not live without it. It finally got so bad her Dr. requested a scope be done. Sure enough she had a hole the size of a softball in her stomach due to the excessive use of OTC drugs. Her specialist told her he absolutely couldn't believe it the day that the FDA approved Alleve for OTC use. He said he has new patients coming in each and every day because of this. He also told her the combo she was taking was basically lethal. Fortunately for her, she was able to repair her stomach and is now healthy. Had the treatments not worked, she was looking at have the lower portion of her stomach removed. Not something anyone thinks about when taking an OTC that we are told by the FDA is a safe thing to do!!!

Food for thought...
Click to view billhalliv's profile Amateur 9 posts since
Dec 14, 2007
19. Aug 10, 2007 1:28 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
I suffered from ITB so badly that I missed my Spring marathon. I was about 1 month away from it when it struck.

I have to say that I was tempted to just cover up the pain with some sort of pain killer just so that I could finish it. It would have been my first marathon, and I REALLY wanted it bad.
I finally got through the beurocracy of my insurance referals and got some really great physically therapy. I have to say that the foam roller was probably the biggest help.

Physical Thereapy would probably be the best thing for you, but if you don't want to wait through the Primary Care Physician referals, doctor's schedules, etc, or even just don't want to spend the money, your best bet is probably to buy a foam roller at your local Target store for about $25.

I have to warn you though... Foam rollers are quite painful when you first start using them. BUT, as impossible as this sounds, after using it regularly for a couple weeks it actually starts to feel good.

Now, I'm on back on schedule for my first marathon in October.

I wish you the best of luck. I'm truly sorry for your situation. I definitely feel your pain

Bill
Click to view ca marathoner's profile Amateur 13 posts since
Jul 10, 2007
21. Aug 11, 2007 3:29 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
In the case of NSAID inhibiting the healing process there are multiple studies some a few are Bruckner P.Clinical Sports Medicine. 1995 P 105 - 109
Greene,J. Cost conscious prescriping of non steriodal anti-inflammatory drugs for adult with arthritis,. Archives of internal medicine 19992 152 - 1995 - 2002
Almekinders,L. An in vitro investigation into the effects of repetitive motion and nonsteriodal anti inflammory medication on human tendon fobroblasts AJSM 1995 23: 119 - 123
Kulick,M Oral ibuprofen: evaluation of its effect on peritendinous adhesioons and the breakage strengthy of a tenorrhaphy. The journal of hand Surgery 1986 11A 100 - 119
There is a difference between pain relief and healing.
Again there are multiple studies on the effects of Omega 3s & 6s and their anti inflammatory capabilities
Two: LeeTH, Hoover RL,Williams JD et al Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function.N Engl J Med 1985: 312 1217 - 1224
Bucci LR Nutrition Applied to injury Rehabilitation and Sports medicine, CRC Press, Boca Raton 1994
Multiple studies exist on glucosamine sulfate and chondroitin sulfate most recent would probabaly be the GAIT study which was a fairly lengthly study the findings were released either last year or the year prior.
The study on cherries is from MSU DR Muraleedharan Nair. I don't have at hand but I am reasonably certain a similar study came out in the last two years either out of Canada or the UK.
Pub med and other related search engines are excellent places to research for the information and make your own informed decision on which way you want to go.
The thought is prolonged excessive use and/or misuse of NSAID demonstrate decreased DNA synthesis ( proliferative step in healing)
inhibit proteoglycan synthesis
GI bleeding and erosion may occur
HTN, CHF,hyperkalemia and renal insufficiency
Increased health costs, morbidity and mortality.
In this country we are too accustom to popping a pill to solve a problem or quick fixes regardless of long term consequences.
Play risk management with your training and racing be objective. Find out the root cause of your injury or reason for " excessive" muscle soreness. It usually is multifactorial.
Be proactive that can start in your warm up I like to use a technique with my runners called reciprocal inhibition stretching as you contract one muscle group the opposite muscle must relax to allow the motion we do everything from the foot on up to the neck. Since using this approach injuries have been reduced by 75% I believe we are correcting muscle imbalancies created from running, it also increases the core tissue temperature when preparing to start an active dynamic warmup.
The use of ice and ice baths particularily post race.
The importance of refueling within 15 min after a training run or race is critical to avoid being in a chronically depleted state. Two really good books are Edmund Burke's Optimal Muscle Recovery and John Ivy's Nutrient Timing this are cutting edge books in the field of performance nutrition.
Other great ideas like using a foam roller, roller ball or knuckler to give yourself periodic massages .
Foods to avoid when in an acute flare Red meat (beef, pork,lamb
Shellfish ( lobster, shrimp, clam)
Dairy (milk, the next one kills me because I am pretty sure i was a moouse in my past lifetime cheese
The above are thought to increase levels of arachidonic acid and proinflammatory agents.
Caffiene coffeee, tea, soda decrease levels of magnesium and calcium
Alcohol ( excessive) decreased levels of magnesium.
Just food for thought.
Click to view AndyHass's profile Legend 1,385 posts since
Dec 14, 2007
22. Aug 11, 2007 9:38 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
I agree, get to the root cause and solve that. Taking anything to mask it does just that...mask the problem and allow it to get worse.

Beware information off the internet. The beauty of the internet is that anyone can research anything. The evil of the internet is that there is no guarantee as to the accuracy and validity of any of the information you find. Even studied on pubmed are subject to false information.....nothing guarantees that studies are well-run or of sufficient sample size or in the appropriate population to tell us anything. For example, despite people touting the benefits of supplemental anti-oxidants no large, well-run study has been able to find any type of measurable positive impact. There's a very long thread further down that's a good demonstration of this.
Click to view ca marathoner's profile Amateur 13 posts since
Jul 10, 2007
23. Aug 11, 2007 9:51 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
You always need to look at research design as there can be bias. But the multitude of research cannot be ignored. I very much doubt that all these researchers are in collusion to mislead the public. I agree we all need to look at internet or any information including that provided analytically . But to dismiss the benefits of healthy sensible nutrition and it's benefits towards health and it's role in injury prevention is ignorant and irresponsible.
Andy which thread are your referring to further down?
Click to view ca marathoner's profile Amateur 13 posts since
Jul 10, 2007
24. Aug 11, 2007 9:59 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
Andy, Found it didn't see at first. I understand where you are coming from. My only intent was to show that with a little effort often times we can do the same things with proper nutrition with equal if not more effectiveness than using pills as in the case of the individual who started this thread using NSAIDs to mask the problem.
Click to view DavidD063's profile Legend 361 posts since
Jan 25, 2007
25. Aug 13, 2007 12:55 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
quote:<HR>Originally posted by Jim24315:
ca marathoner

Which foods have pro-inflamatory properties that should be avoided?

thanks

<HR>


The most powerful pro-inflammatories (foods that can contribute to inflammation) are dairy fats and omega-6 fats (vegetable oils).

The more potent natural anti-inflammatories include fish oil.
Click to view DavidD063's profile Legend 361 posts since
Jan 25, 2007
26. Aug 14, 2007 12:41 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
Another pro-inflammatory factor is increased body fat
Click to view Harper028's profile Pro 191 posts since
Jan 20, 2007
27. Aug 14, 2007 4:18 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
I take Aleve b/c it works, and only when I have some kind of minor injury. My left hip flexor muscles were bothering me during my half marathon Sunday. Afterwards I decided on a week-long course of Aleve and ice. I recovered from my race just fine; I wouldn't say the NSAIDs inhibited my recovery. In general I don't put too much confidence in "studies."

I agree whole-heartedly that a healthy diet is the most overlooked aspect of training. I eat a lot of vegetables, a little meat (good iron & protein), lots of beans, quinoa and only whole-grain pasta. Plus fruits. Everything low-glycemic; I avoid simple sugars and saturated fats.
Click to view DavidD063's profile Legend 361 posts since
Jan 25, 2007
28. Aug 14, 2007 11:25 PM in response to: xWeaselx
Re: Anti-inflammatory medicine
quote:<HR>Originally posted by Harper:
I take Aleve b/c it works, and only when I have some kind of minor injury. My left hip flexor muscles were bothering me during my half marathon Sunday. Afterwards I decided on a week-long course of Aleve and ice. I recovered from my race just fine; I wouldn't say the NSAIDs inhibited my recovery. In general I don't put too much confidence in "studies."

I agree whole-heartedly that a healthy diet is the most overlooked aspect of training. I eat a lot of vegetables, a little meat (good iron & protein), lots of beans, quinoa and only whole-grain pasta. Plus fruits. Everything low-glycemic; I avoid simple sugars and saturated fats.
<HR>


You take a drug because it "works" -- meaning you don't feel the problems you have? I like your diet, it's very anti-inflammatory (and reminded me that insulin also stimulates inflammation). But a week of NSAIDs? Wow, what a stress on the body's chemistry. You have no idea how much they inhibited your recovery.

No confidence in studies? That's how all the NSAIDs got to the market. Basically, the drug companies looked at how the body and various plants and oils controlled inflammation, and they copied what natural already did, and BINGO...here are a whole line of drugs...complete with dangerous side effects.

Don't mean to be so hard on you, but stick to your diet. You have all you need there.
Click to view Tchuck's profile Legend 554 posts since
Dec 14, 2007
29. Aug 15, 2007 8:20 AM in response to: xWeaselx
Re: Anti-inflammatory medicine
quote:<HR>Originally posted by xWeaselx:
What's the best over the counter Anti-inflammatory medicine I could get at a local drug store? I'm running my first half-marathon tomorrow and want to get something. I've been told Advil is pretty good but was wondering if there was anything better? Thanks<HR>


Below is a natural and very effective pain/inflammation reliever.

http://www.europharmausa.com/proddetail.asp?CID=16[/URL" target="_blank">

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