I'm by no means a lifting expert, but I'm moderately good at running, and here's my routine:
Monday: no running, chest/core/back weights
Tuesday: speedwork (usually 6 x 1 mile repeats), bis/tris/delts/abs weights
Wednesday: tempo run 6 to 10 miles, no lifting
Thursday: no running, same lifting at Monday
Friday: easy middle-long run of 10 to 15 miles, same lifting as Tuesday
Saturday: no running, no lifting
Sunday: long run of 20 to 40 miles, no lifting
So, I'm lifting four days a week and running four days a week - only doing both on Tuesdays & Fridays. Only have two weight workouts (3 sets of 12/10/8 reps) and neither have anything "below the waist".
I by no means have large muscles, but at less than 5% bodyfat, what I do have looks pretty good (42 and have a great six-pack!

)
If you're coming at this from the bodybuilder angle, then you're probably well versed in the nutrition aspects of fitness - keep in mind that running is burning up 120 or so calories per mile, so it's easy to start losing mass if you're not making up for that increased energy output.
Good luck!
kestrou