Best of Luck to both of you, I ran Boston 2006, it was a great race. I assume you are starting in the first wave? My advice to you would be to ride the bus to the start, the ride isn't that long, and the athletes village is pretty nice. Enjoy the walk to the starting line, take in the excitement in the air, and focus on the task at hand. IMO, the course isn't that nasty. Stay on pace, have patience, there are going to be people flying down the hill in the first 5 miles, don't go with them, they will come back. Enjoy the girls in the scream tunnel, I think you can hear them half a mile away!, but fight the urge to throw a surge in pace in there. Once you hit mile 16? I believe, you will start going up the first of the three hills, ending with "Heartbreak Hill". If you stuck with your pace to this point, by the time you get to the last one, you'll be in good shape, and it's pretty much a downhill run from there, with a nice downhill at mile 21-22, look for the Citgo sign, check your watch, and go for it, you have enough miles left to make a move, and it's mostly downhill. You might surprise yourself with your time if you run smart.
Best of Luck, I'll keep my eye on the results to see where you ended up.
Boston Marathon 2006 - 2:53:46